About 10.50am, police arrested a 48-year-old man during a car stop at George Booth Drive, Sea Hampton.
He was taken to Toronto Police Station where he is assisting with inquiries.
His car was seized for forensic examination.
Tactical Operations Unit officers stopped a second vehicle in Forest Rd, Wyee, about 1.20pm and arrested a 24-year-old man. His car was also seized by police.
A 17-year-old girl was arrested a short time later in nearby Wyee St.
Police will allege Jesse Thompson and a friend were pursued following a possible road rage incident and cornered in Byron St, Wyong, just before 12.30pm yesterday.
It is alleged a gunman, in a white Mitsubishi Triton, approached the Toyota Kluger in which Mr Thompson was a passenger and shot him in the neck.
Flash burns on the 19-year-old’s skin suggested the shot was fired at close range, with the 28-year-old driver, who escaped with only injuries, hit in the hand.
“About 1.20pm, police arrested a man after a vehicle stop on Forest Rd in Wyee,” a NSW Police spokesman said today.
“He was taken to Wyong police station where he is assisting with inquiries.”
NSW Police sources confirmed the man in custody was wanted in relation to the murder of Mr Thompson.