Symons has been dealt a blow with the overnight death of his son Samuel.
Samuel, 27, had recently been receiving treatment after the recurrence of an aggressive brain tumour, diagnosed when he was four.
“It is with the deepest sadness Red announces the passing of his beautiful son Samuel Symons,” a statement from 3AW said.
“Samuel passed away peacefully overnight surrounded by his family. We ask that you please respect the privacy of Red and his family at this very sad and difficult time.”
In June, Symons told the Herald Sun that Samuel had received some good news after undergoing further treatment for the tumour.
“The result has been good,” Symons said. “However the simple truth is, and anyone who has cancer knows this, it never really goes away.”